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Treatment-Resistant Depression Has a New FDA approved treatment

Treatment-Resistant Depression Has a New FDA approved treatment

 

SPRAVATO™ (Esketamine) – New FDA approved treatment for Treatment-Resistant Depression

March 5, 2019 was a banner day in the fight against depression, anxiety, and other serious mood disorders. For the first time in 30 years, the FDA approved a radical new treatment option for individuals suffering from treatment-resistant depression. This new FDA-approved treatment—SPRAVATO™—is based on years of scientific and anecdotal evidence indicating that ketamine, a well-known anesthetic, may offer an effective treatment for depression when delivered in extremely low doses. SPRAVATO™, developed by the Janssen Pharmaceutical Companies of Johnson and Johnson, is not actually ketamine, in fact, but is a nasal spray of a ketamine derivative known as esketamine.

The push in the medical and scientific communities to develop an FDA-approved, ketamine-based treatment option has been growing for several years. After all, ketamine has been safety and effectively utilized as an anesthetic by physicians and veterinarians since 1970. For example, one of the most highly publicized instances of ketamine usage occurred in 2018, when ketamine was used to sedate 13 members of a Thai youth soccer team who had become trapped deep within a flooded cave system, enabling their successful rescue. Over the past decade, physicians and psychiatrists have been seeing extremely successful results using low doses of ketamine “off label” in the treatment of mood disorders such as depression and anxiety.

The first sign that the FDA was nearing approval of a ketamine-type treatment option came on February 12, 2019 when The FDA’s Psychopharmacologic Drug Advisory Committee and the Drug Safety and Risk Management Advisory Committee together voted that the benefits of the esketamine nasal spray far outweighed the potential risks for patients living with treatment-resistant depression. This vote stemmed from the results of five Phase 3 studies on SPRAVATO™, all of which demonstrated that the treatment offered “statistically significant” and “clinically meaningful” improvement of depressive symptoms both in the short term and over a sustained timeframe. Moreover, these studies indicated that the treatments were well-tolerated with only generally mild and short-term side effects. Janssen noted in its application that if approved, continued evaluation of the risks and side effects of the treatment would continue through a robust Risk Evaluation and Mitigation Strategy (REMS).

How Does SPRAVATO Work?

SPRAVATO-FDA-Approves-Esketamine-Nasal-Spray-For-Hard-To-Treat-Depression-300x263 Treatment-Resistant Depression Has a New FDA approved treatment Los Angeles California Online PharmacySPRAVATO™ is a nasal spray through which a low dose of esketamine is absorbed through the lining of the nasal passages into the blood stream. In scientific terms, esketamine is the s-enantiomer of ketamine; because ketamine is a mixture of two enantiomers (or mirror image molecules), esketamine is literally half of the chemical compound known as ketamine. However, it appears to impact the chemistry of the brain in the same way that ketamine does.

Scientists are still studying the exact mechanism by which esketamine (and ketamine) stimulate relief from depressive symptoms. The most current theory is that both esketamine and ketamine are N-methyl-D-aspartate (NMDA) receptors; in other words, esketamine prevents the brain from incorrectly absorbing glutamate, a neurotransmitter that controls the number of brain synapses. Restoring the proper balance of glutamate quickly establishes the correct balance of neurotransmitters needed for a healthy and well-functioning brain, providing a rapid and effective decrease in depressive symptoms and even suicidal ideation.

SPRAVATO™ is FDA approved for use by individuals with treatment-resistant depression, who have not responded positively to two or more different oral antidepressants (in correct dosages and durations). It is meant to be taken as a supplement to a daily oral antidepressant. While the nasal spray is self-administered, it can only be taken while under close medical supervision in a certified SPRAVATO™ treatment center. During treatment, the patient is closely monitored for a minimum of two hours by a healthcare professional for both effectiveness and potential side effects. As with any medication, it is important to discuss all medications you take and your complete medical history before starting a SPRAVATO™ treatment.

For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online-refill-button Treatment-Resistant Depression Has a New FDA approved treatment Los Angeles California Online Pharmacy

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.

Your Compound Pharmacy to Buy Cialis (Tadalafil) Generic

Your Compound Pharmacy to Buy Cialis (Tadalafil) Generic

Generic Cialis, known as tadalafil, is now available at American Integrative Pharmacy. This is the latest erectile dysfunction drug to go generic in recent times.

Buy-Cialis-Tadalafil-Generic-online-300x300 Your Compound Pharmacy to Buy Cialis (Tadalafil) Generic Los Angeles California Online PharmacyJust some time ago, Viagra (sildenafil) went generic, and prices for sildenafil have been dropping ever since. Chances are that the same will happen with tadalafil.

Tadalafil has come off patent, and at American Integrative Pharmacy (AIP), we are able to compound sublingual troches which are faster acting than its counterpart and much less expensive.

Cialis, which normally wasn’t covered by insurance, and could cost previously upwards of $800 for a 30-day supply is now much more affordable at AIP compounding pharmacy. For the treatment of Erectile Dysfunction, Cialis is the most popular medication.

American Integrative Pharmacy (AIP), led by Dr. Neema Yazdanpanah, provides compounded medications to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

What will Generic Cialis Cost?

In general, generic medications initially appear on the market at a significantly reduced price in comparison to the brand. Unlike the brand, generic medication prices usually decrease rapidly. Many generic versions of prescriptions can become quite affordable within a year of release, especially if multiple manufacturers are producing the generic.

The most common prescription for Cialis, which is thirty tablets, is presently around $800. According to latest estimates, the same quantity of tadalafil will now cost much lesser in its compounded version from American Integrative Pharmacy.

Two points to remember are as follows: Generic drugs are more likely to be covered by insurance, which means that patients may have a much lesser out-of-pocket cost if they are insured.

Generic prices tend to reduce rapidly. Many generic drugs drop by around 50 percent of the brand price after more than one manufacturer enters the market increasing competition.

Synopsis

Tadalafil is a reversible phosphodiesterase Type 5 (PDE5) inhibitor. This medication has been approved for the treatment of erectile dysfunction (ED).

The PDE5 inhibitors (including sildenafil [Viagra] and vardenafil [Levitra]) are a class of drugs that enhance erectile response to sexual stimulation by increasing blood supply to the penis. Tadalafil has a longer duration of action compared to sildenafil or vardenafil.

Safety

Tadalafil generally has few side effects unless it is taken along with other medications. Due to tadalafil’s long duration of action, patients experience its effects for a longer period than with sildenafil or vardenafil.

Tolerance

Headache (11 to 15 percent) and dyspepsia (8 to 10 percent) are the most common dose-related side effects of tadalafil. Around 5 to 6 percent of men reported back pain, initiating 12 to 24 hours after the dose and lasting for up to 48 hours.

Efficacy

The primary outcomes of the treatment of erectile dysfunction with tadalafil are attaining an erection, successful intercourse, and overall satisfaction with sexual function.

Ease of Use

Tadalafil dose is usually 10 mg, which is to be taken no more than once daily by mouth, at least 30 to 60 minutes prior to sexual activity. The effects of the medication may last for up to 36 hours, and the dose can be increased to 20 mg if required.

Bottom Line

Tadalafil effectively enhances the ability of males with ED to attain an erection and successfully complete intercourse, similar to other PDE5 inhibitors. In some men with ED due to diabetes, tadalafil is less effective but still useful. Its longer duration of action may require less frequent dosing, and the user may be able to take it earlier in the day of planned sexual activity.

American Integrative Pharmacy offers both modern and traditional compounding solutions, including online prescription refills, to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

 For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online-refill-button Your Compound Pharmacy to Buy Cialis (Tadalafil) Generic Los Angeles California Online Pharmacy

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.

Is Generic Cialis available now?

Is Generic Cialis available now?

Is Generic Cialis available now?

cialis-guide-300x240 Is Generic Cialis available now? Los Angeles California Online PharmacyYes, it’s called tadalafil and is over 50% cheaper than brand-name Cialis. Compared to the brand, which can cost between $350 and $1700 for 30 tablets depending on their strength, generic tadalafil costs between $100 and $600 for 30 tablets.

Is Tadalafil and Cialis the same thing?

Cialis is the brand name for tadalafil, a drug used to treat erectile dysfunction. It is similar to Viagra and Levitra. Under the brand name Adcirca, tadalafil is used for pulmonary arterial hypertension.

Do I need a prescription for Cialis or Tadalafil?

Yes. Cialis / tadalafil is approved by the FDA to treat erectile dysfunction (ED). Your doctor can prescribe Cialis (or the generic version tadalafil) 5mg, 10mg, and 20mg. The starting dose we generally recommend is 10mg.

What is the average cost of Tadalafil?

It is available in both brand and generic versions. Cialis is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost. The lowest average price for the generic version of Cialis (tadalafil) is around $30 – $35, 89% off the average retail price of $313.35.

How Long Does Generic Cialis / tadalafil last?

How long varies with the drug. Viagra and Levitra take about 30 minutes to work, and the effects last for about 4 hours after you take the pill. You should take Cialis at least 2 hours before you plan to have sex. The effects may last for up to 36 hoursafter you take it.

For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online-refill-button Is Generic Cialis available now? Los Angeles California Online Pharmacy

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.

Possible Tadalafil (Erectile Dysfunction Prescription Medication) Side Effects

Possible Tadalafil (Erectile Dysfunction Prescription Medication) Side Effects

shutterstock_66078535-copy-e1559176601474-300x240 Possible Tadalafil (Erectile Dysfunction Prescription Medication) Side Effects Los Angeles California Online PharmacyTadalafil use may lead to side effects such as stomach upset, headache, muscle pain, dizziness, stuffy nose, or flushing. In case any of these side effects persist or worsen, patients should promptly contact their doctor or pharmacist.

It’s prudent to rise slowly from a sitting or lying position to mitigate the risk of dizziness and lightheadedness.

 

Key Positives

Patients should remember that their doctor has prescribed this drug since they have determined that the benefits outweigh the risk of side effects for the patient. Many men using this drug do not experience significant side effects.

American Integrative Pharmacy (AIP), led by Dr. Neema Yazdanpanah, provides compounded medications to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

 

Rare Side Effects and Complications

Sexual activity may cause extra strain on the heart, especially in men with heart problems. Patients with heart problems who experience any of these serious side effects during sex should stop and seek medical attention immediately: fainting, severe dizziness, nausea, chest/jaw/left arm pain.

In rare cases, a sudden decrease in vision, including permanent blindness, in one or both eyes (NAION) may happen. In case of this serious problem, the patient should discontinue using tadalafil and seek medical attention immediately.

Patients with diabetes, heart conditions, high cholesterol, specific eye issues (“crowded disk”), and high blood pressure have a higher possibility of developing NAION. The chances of this side effect occurring are also higher for men over 50 years of age and those who smoke.

In exceptional cases, the patient may experience a sudden reduction or loss of hearing, at times along with ringing in the ears and dizziness. In case this happens, they should discontinue tadalafil and seek medical help immediately.

In the rare scenario that a patient has a prolonged or painful erection lasting for four hours or more, they should stop taking this medication and seek medical help promptly, or permanent problems may develop.

It is rare for patients to experience a very serious allergic response to this medication. But patients experience any of the following symptoms of a serious allergic response should seek medical attention right away: itching/swelling (especially of the tongue/throat/face), rash, trouble breathing, severe dizziness.

 

Cialis – Who should not take it?

In exceptional cases, Cialis can impede the blood supply to the optic nerve of the eye, leading to a sudden loss of vision. The possibility of this side effect is higher in patients with diabetes, hypertension, pre-existing eye conditions, heart disease, or high cholesterol.

Individuals with the below mentioned conditions should avoid taking Cialis unless a doctor agrees:

  • high or low blood pressure
  • heart rhythm issues, angina, or any type of heart condition
  • structural deformity of the penis, such as Peyronie’s disease
  • liver or kidney disease
  • retinitis pigmentosa
  • congestive heart failure or stroke within the past six months, or myocardial infarction within the past three months
  • multiple myeloma, sickle cell anemia, hemophilia, leukemia, or another blood condition
  • stomach ulcer
  • any health condition for which they have been advised not to have sexual intercourse

 

Cautions

The FDA has issued warnings related to sudden hearing loss in individuals using tadalafil and similar drugs.

The FDA announced in 2016 that they were assessing the need for regulatory action after indications that the use of Cialis and similar medications might lead to an increase in the risk of melanoma skin cancer. But some researchers have questioned the seriousness of this risk.

American Integrative Pharmacy offers both modern and traditional compounding solutions, including online prescription refills, to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.


For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online-refill-button Possible Tadalafil (Erectile Dysfunction Prescription Medication) Side Effects Los Angeles California Online Pharmacy

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.

The Most Common Tadalafil Brands Prescribed For Erectile Dysfunction Are Cialis And Adcirca

The Most Common Tadalafil Brands Prescribed For Erectile Dysfunction Are Cialis And Adcirca

shutterstock_138727886-300x199 The Most Common Tadalafil Brands Prescribed For Erectile Dysfunction Are Cialis And Adcirca Los Angeles California Online PharmacyCialis is the brand name for tadalafil, which is a medication used in the treatment of erectile dysfunction. Similar to Viagra and Levitra, tadalafil is used to treat pulmonary arterial hypertension under the brand name Adcirca.

Cialis enhances the blood supply to the penis, which enables a man to attain an erection. However, it does not cause sexual arousal. This drug should be used with caution and only under the supervision of a medical professional.

The Food and Drug Administration (FDA) approved tadalafil for the treatment of erectile dysfunction (ED) in the US in 2003. This medication is also used in the treatment of arterial hypertension and benign prostatic hyperplasia (a condition where the prostate gland becomes enlarged, leading to issues in urination).

American Integrative Pharmacy (AIP), led by Dr. Neema Yazdanpanah, provides compounded medications to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

 

How it Works

Cialis is a commonly tadalafil product used to treat erectile dysfunction or ED. A man attains an erection when the penis fills with blood. This occurs as the blood vessels that supply blood to the penis dilate, enhancing the blood supply.

At the same time, the blood vessels that remove blood from the penis constrict. The blood collects in the penis, and this leads to an erection.

Upon becoming sexually stimulated, the male body releases nitric oxide into the penis. Nitric oxide facilitates the production of cGMP, which manages the dilation and constriction of the blood vessels that supply blood to and from the penis.

PDE5 is another substance that destructs cGMP. When this happens, the blood vessels return to their normal size, and the erection ends. Tadalafil prevents PDE5 from destructing cGMP, which helps the erection sustain for a longer period.

PDE5 is also found in the muscles of the arteries in the walls of the lungs. Due to this reason, the same medication can be used in the treatment of pulmonary hypertension.

 

Benefits

Cialis is available in film-coated, yellow, and almond-shaped tablets in 5, 10 and 20 milligram (mg) doses.

Patients with ED can take Cialis as necessary. However, it should not be taken more often than once every 24 hours.

This medication will work only when a man is sexually aroused. The drug cannot help a man attain an erection in the absence of sexual stimulation.

The initial dose of 10 mg should be taken at least 30 minutes prior to sexual activity. Depending on how the patient responds, the dosage can be adjusted. A single dose can be a maximum of 20 mg.

The patient should not take more than one dose within a 24 hour period. However, a daily dose of 10 mg to 20 mg is not recommended. The reason for this is that remnant of the medication remains in the body for at least 24 hours.  

Patients who are sexually active at least twice weekly can take a daily dose of 5 mg. Depending on the patient’s response, the doctor may reduce this dose to 2.5 mg once daily.

Tadalafil for ED is only for use by adults who are 18 years of age or older.

 

Side Effects

Taking tadalafil or Cialis along with nitrate drugs can lead to a serious and sudden decrease in blood pressure (hypotension). Men using a nitrate medication prescription for heart conditions or chest pains should not take tadalafil.

Priapism is a condition in which the erection lasts for more than four hours. This can be damaging to the penis. Patients should seek prompt medical attention if this occurs.

American Integrative Pharmacy offers both modern and traditional compounding solutions, including online prescription refills, to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online-refill-button The Most Common Tadalafil Brands Prescribed For Erectile Dysfunction Are Cialis And Adcirca Los Angeles California Online Pharmacy

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.

What is Tadalafil is Used to Treat Erectile Dysfunction

What is Tadalafil is Used to Treat Erectile Dysfunction

shutterstock_552011107-300x200 What is Tadalafil is Used to Treat Erectile Dysfunction Los Angeles California Online PharmacyTadalafil is an effective treatment for male sexual function issues, such as impotence or erectile dysfunction-ED. Tadalafil works, along with sexual stimulation, to increase the blood supply to the penis enabling a man to get and maintain an erection.

In addition, Tadalafil is also used to address enlarged prostate symptoms (benign prostatic hyperplasia-BPH). This medication offers relief from BPH symptoms such as problems in starting urination flow, weak stream, and the need to urinate urgently or frequently (including during night time).

Tadalafil is believed to work by relaxing the smooth muscle in the bladder and prostate. This medication does not offer protection against STDs such as hepatitis B, HIV, gonorrhea, and syphilis.

American Integrative Pharmacy (AIP), led by Dr. Neema Yazdanpanah, provides compounded medications to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

 

How to use Tadalafil

Before starting tadalafil and each time they get a refill, patients should read the Patient Information Leaflet provided by their pharmacist. In case of questions, consult your doctor or pharmacist.

This medication is to be taken by mouth, with or without food, as directed by the physician. Patients should not take tadalafil more than once a day.

The dosage will be based on a patient’s specific condition, response to treatment, and other drugs they may be taking.

If the patient is also taking finasteride in combination with this drug to address BPH symptoms, they should consult their doctor on how long they should continue taking this medication.
Tadalafil may be prescribed in two ways to address erectile dysfunction-ED. The doctor will determine which way is most appropriate for the patient to take tadalafil.

Patients should follow their doctor’s instructions exactly as their dosage depends on how they are taking it. The first way to take this drug is to take it as required, typically at least 30 minutes prior to sexual activity. The effect of tadalafil on sexual ability may sustain for up to 36 hours.

The second method to treat ED is to take tadalafil on a regular basis, once daily-every day. Patients taking it in this manner may attempt sexual activity at any time between their doses.

Patients taking tadalafil to treat ED as well as BPH should take it as instructed by their physician, typically once daily. They may attempt sexual activity at any time between their doses.

If the patient takes tadalafil one time a day for BPH, or for ED, or for both, they should take it routinely to derive the most benefit from this medication. It can be helpful to take it at the same time each day to help remember to take it.

 

Side Effects

Some patients may experience back pain, headache, stomach upset, stuffy nose, muscle pain, dizziness, or flushing. In case such effects persist or become worse, the patient should promptly contact their doctor or pharmacist.

The patient should rise slowly from a sitting or lying position to reduce the risk of lightheadedness and dizziness.

It is important for patients to remember that their doctor has prescribed this drug as they believe that the benefit outweighs the risk of side-effects for the patient. Many individuals on this medication do not experience significant side-effects.

American Integrative Pharmacy offers both modern and traditional compounding solutions, including online prescription refills, to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.
For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online-refill-button What is Tadalafil is Used to Treat Erectile Dysfunction Los Angeles California Online Pharmacy

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.

Top Nutrient Deficiencies in Thyroid Disease Patients

Top Nutrient Deficiencies in Thyroid Disease Patients

shutterstock_354175895-300x200 Top Nutrient Deficiencies in Thyroid Disease Patients Los Angeles California Online PharmacySmooth thyroid function depends on various vitamins and minerals working together.

Multiple sources indicate that the following nutrients may all be involved in either initiating thyroid dysfunction or helping in managing symptoms through maintaining appropriate levels: vitamin D, thiamine (B1), protein, vitamin A, cobalamin (B12), riboflavin (B2), selenium, iodine, vitamin C, magnesium, iron, and zinc.

The following sections contain information on a few of these nutrients and their thyroid-related functions in the body as well as details on the best dietary sources or other ways of repletion.

American Integrative Pharmacy (AIP), led by Dr. Neema Yazdanpanah, provides compounded medications to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

 

Vitamin D

Vitamin D is considered to be an “immune modulator.” Autoimmunity is related to an imbalance between the two portions of our immune system called Th-1 (cell-mediated) and Th-2 (humoral).

Therefore, it is logical that vitamin D deficiency has been found to be more pervasive among people with autoimmune thyroid conditions in comparison to healthy individuals.

The patient’s integrative medical care professional can test and monitor their levels of vitamin D. They can offer guidance on supplementation. People with autoimmune thyroid conditions are reported to have the best results if they maintain their vitamin D levels between 60 and 80 ng/L.

 

Vitamin B12

According to estimates, around 40 percent of hypothyroid patients have a vitamin B12 deficiency.

This deficiency may be related to hypothyroidism due to the autoimmune link. Other reasons for the deficiency may include poor dietary habits, gut infections, and digestive dysfunction.

The most absorbable form of supplemental B12 is sublingual (after injections). Thyroid patients should ideally have B12 levels between 700-900 pg/ml.

 

Iodine

Iodine is a trace mineral, which is typically associated with thyroid dysfunction. Iodine is necessary for the manufacture of the thyroid hormone, T4. Between 70 to 80 percent of iodine in the body is located within the thyroid gland.

The deficiency of iodine can lead to weight gain, sluggishness, and other symptoms of hypothyroidism. In extreme cases, the patient may develop a goiter (enlarged thyroid).

Iodized salt, sea vegetables such as seaweed, Swiss chard, spinach, and lima beans are good sources of iodine in foods.

As excessive amounts of iodine can be problematic, supplementation should only begin after iodine level testing and under the guidance of an experienced thyroid practitioner.

Iodine can, at times, lead to a flare-up of symptoms. Therefore, it is important to exercise caution in autoimmune thyroid conditions.

 

Selenium

Selenium is also a trace mineral, which is vital for thyroid function as it is necessary for the conversion of T4 to T3 (inactive to an active form of thyroid hormone).

According to some research on selenium, supplementation may reduce thyroid antibodies in people with Graves’ disease and Hashimoto’s thyroiditis.

In some studies, taking 200 mcg of selenium on a daily basis has been proven effective in reducing TPO antibodies by 50 percent within three months. Other research does not offer similar clarity related to supplementation in thyroid patients.

Irrespective of this, it is important to have optimal levels of selenium for overall health due to its part in the immune function.

American Integrative Pharmacy offers both modern and traditional compounding solutions, including online prescription refills, to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.
For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online-refill-button Top Nutrient Deficiencies in Thyroid Disease Patients Los Angeles California Online Pharmacy

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.

Ketamine Nose Spray is Used For Pain Management

Ketamine Nose Spray is Used For Pain Management

shutterstock_1020732736-300x205 Ketamine Nose Spray is Used For Pain Management Los Angeles California Online PharmacyA majority of individuals will experience mild or severe type of pain due to some reason in the course of their lifetime.

Severe or persistent pain can debilitate an individual and impede their performance of routine activities. If such pain becomes chronic, it can significantly impact the quality of a person’s life.

The patient will struggle to complete routine work and household tasks, and find it challenging to concentrate on anything because of persistent pain.

Chronic pain can occur due to various reasons, and it can usually be challenging to manage this pain for an extended time with conventional pain medicines and anti-inflammatory drugs.

 

Pain Relief with Ketamine

Many patients experiencing pain from syndromes seek relief by using steroids, muscle relaxants, and opiates. These may have unpleasant side-effects and can carry unpleasant side effects. Ketamine nasal spray could be an effective solution for many patients amid the extensive problem of pain syndromes.  

Ketamine nasal spray compounding pharmacy treatment is proven to be safe and effective while offering quick relief from symptoms. Ketamine also does not create the unpleasant side-effects often associated with conventional pain drugs.

The patient can easily acquire ketamine nasal spray if they have a prescription from licensed medical care professional. Patients can accomplish sustainable chronic pain relief with a low dose, controlled treatment regimen with ketamine.

American Integrative Pharmacy (AIP), led by Dr. Neema Yazdanpanah, provides compounded medications to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

 

Ketamine Benefits

A key issue with chronic physical pain is that it can take on a psychological dimension over a period. In some instances, it can also cause the onset of depression.

Ketamine treatment provides patients with a unique advantage in these circumstances by addressing the physical pain as well as the depression symptoms simultaneously.

A main characteristic of ketamine is that it can obstruct and reset pain receptors in the brain and create a balance between neurons and hormones by modifying glutamate and GABA levels.

When the ketamine expert delivers ketamine nasal spray in low, controlled dosages, it can treat physical pain along with the psychological discomfort caused due to the chronic pain.

 

Pain Syndrome Management with Ketamine

Complex Regional Pain Syndrome (CRPS), also called Reflex Sympathetic Dystrophy (RSD), refers to a chronic pain condition that may become worse if it remains untreated.

In most cases, the pain initially occurs in the arm or leg and slowly spreads to other locations. CRPS is a very painful condition, which has a score of 42 out of 50 on the McGill pain scale.

An increase in the number of NMDA receptors intensifies the pain as the pain signals are amplified. Ketamine treatment can be very effective in such cases as it impedes the NMDA receptors. Ketamine will naturally obstruct and reset the pain signal process. This offers pain relief in a situation where other treatments have been ineffective.

NMDA receptor obstruction prevents the pain from reaching the brain and the spinal cord. As a result, the central pain centers are rebooted and get desensitized to peripheral pain signals.

American Integrative Pharmacy offers both modern and traditional compounding solutions, including online prescription refills, to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.
For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online-refill-button Ketamine Nose Spray is Used For Pain Management Los Angeles California Online Pharmacy

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.

Ketamine Nose Spray Used For Depression

Ketamine Nose Spray Used For Depression

shutterstock_504503152-300x200 Ketamine Nose Spray Used For Depression Los Angeles California Online PharmacyKetamine nose spray is used for pain as well as a safe and effective compounding pharmacy treatment for depression. This dosage method may offer fast relief for difficult to treat depression.

American Integrative Pharmacy (AIP), led by Dr. Neema Yazdanpanah, provides compounded medications to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

 

How does Ketamine Nasal Spray Work?

Within its cavity, the nose has nerve fibers that connect directly to the brain stem. Therefore, they bypass the blood-brain barrier. The tight junctions of cells obstruct most medications delivered through the bloodstream from the brain.

But administering the medication through the nasal cavity is a dependable way to deliver many useful medications, including oxytocin, ketamine, flumazenil, HCG, fentanyl, sermorelin, vitamin b12, and various other large peptide analogs.

This method is particularly effective for the use of ketamine as an anti-depressant. The effect of ketamine in the brain is to impede the NMDA [N-methyl-d-aspartate] glutamate receptor offering a quick response time.

 

Customized Strength and Dosage

A compounding pharmacy can develop ketamine spray in various strengths. However, the solubility of the drug is limited at 200mg/ml. It is vital to keep this strength at room temperature or otherwise it may precipitate out of solution.

Compounding pharmacists use preserved water in their formulations for minimal risk of bacterial contamination. The most commonly used concentration is 100mg/ml.

While dosages differ extensively, each pump of the spray bottle is 0.1ml. Therefore, each pump delivers 10 mg of ketamine. Patients should consult their doctor to discuss dosing. Many times, even a single dosage offers a dramatic turnaround.

 

Reduced Side Effects

Many antidepressants are associated with multiple side-effects. However, ketamine appears to have a remarkably safe profile with limited side effects. In addition, the two to three times a week dosage schedule offers an easy, discreet dosage schedule.

The National Public Radio (NPR) recently did a story on ketamine for depression. The researchers’ experience with this treatment is in alignment with the view of compounding pharmacists who feel that ketamine nasal spray is an effective treatment for pain management and depression.

Ketamine can be a remarkably effective therapy. However, the patient will require a prescription from a licensed health care professional for this treatment option.  

 

Ketamine for the Treatment of Depression

Ketamine use for the treatment of PTSD and as an anti-depressant is increasing rapidly. Additionally, research studies are becoming more detailed.

A 2014 article by BBC on ketamine reports that some patients experiencing untreatable depression for several years felt the disappearance of symptoms within some hours of taking low doses of ketamine.

It is very effective in depression treatment as its positive effect commences almost immediately within one to 12 hours. On the other hand, SSRIs may take many weeks to be effective, if at all. Additionally, ketamine appears to have lesser side-effects than SSRIs (although there have been no studies on the use of ketamine in the long-term).

Ketamine therapy is very effective for people who do not respond to SSRIs and other anti-depressants. In case a patient has experienced limited success with various other treatments, they may be responsive to ketamine.

CBD oil may also offer benefits for the management of pain and depression. This treatment can be used in combination with ketamine nasal spray.

American Integrative Pharmacy offers both modern and traditional compounding solutions, including online prescription refills, to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.


For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online-refill-button Ketamine Nose Spray Used For Depression Los Angeles California Online Pharmacy

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.

What is Ketamine Nasal Spray prescriptions used for?

What is Ketamine Nasal Spray prescriptions used for?

shutterstock_354175895-300x200 What is Ketamine Nasal Spray prescriptions used for? Los Angeles California Online PharmacyThe American Foundation for Suicide Prevention reports that suicide is the tenth leading cause of death in the US. A dismaying 44,965 individuals die as a consequence of suicide annually in the country. The Foundation also states that on average 123 suicides take place daily.

Prescription ketamine nasal spray is emerging as one of the promising compounding pharmacy treatments for depression and anxiety.

American Integrative Pharmacy (AIP), led by Dr. Neema Yazdanpanah, provides compounded medications to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

 

Research Supports Efficacy of Ketamine Nasal Spray

According to a study published last year, there is a rise in recorded cases of depression in the US. These statistics call for more robust prevention strategies and more effective treatments for major depression.

Researchers from Janssen Research & Development and Janssen Scientific Affairs (based in Titusville, NJ, and San Diego, CA) have collaborated with colleagues from the Yale School of Medicine (based in New Haven, CT) have been studying a faster-action medication for individuals who are at imminent risk for suicide.

Recently, first author Dr. Carla Canuso and colleagues undertook a proof-of-concept, phase II, double-blind study to test the efficacy of an esketamine nasal spray for people in need of fast relief from the symptoms of severe depression and suicidal ideation.  

Esketamine refers to a type of ketamine molecule that contains anesthetic and anti-depressive qualities. However, unlike ketamine, it appears to cause fewer side-effects, such as hallucinations, making it a possible solution for the treatment of major depression.

The results of the new study have been published in The American Journal of Psychiatry, and they indicate that this innovative nasal spray offers effective short-term results for people who are at high risk for suicide.

 

A Fast and Effective Newcomer?

The researchers worked with 68 participants with severe depression symptoms in their phase II trial. These participants were divided randomly into two grows. The first group was assigned esketamine spray treatment while the second one was given a placebo.

The participants received their assigned treatment twice weekly for four weeks. All volunteers also followed their routine depression therapy for the duration of the study.

Dr. Canuso and colleagues monitored the impact of the assigned treatment in three stages:

  • at 4 hours
  • at 24 hours
  • at 25 days after initial administration

The people who had been assigned the esketamine nasal spray saw a significant improvement in the symptoms of depression at 4 and 24 hours following treatment in comparison to volunteers in the placebo group.

In a similar manner, there was a significant improvement in suicidal ideation in participants in the esketamine spray group after four hours.

When analyzing the potential side-effects, Dr. Canuso and team observed that the most common side-effects for people who took esketamine included dizziness, disassociation, nausea, and headaches.

Further to these outcomes, the researchers conclude that intranasal esketamine could be a useful, viable treatment for people at high risk of suicide as traditional antidepressants may take between four to six weeks to start working.  

Dr. Canuso and colleagues acknowledge the need for more research as there is a potential risk that this intranasal spray may lead to ketamine overuse.

 

Final Testing

The researchers aim to make this drug available in the market eventually. Before that, however, the spray must undergo a phase III trial prior to requesting FDA-approval.

Janssen Research & Development, a pharmaceutical company in the Johnson & Johnson family, funded the study.

American Integrative Pharmacy offers both modern and traditional compounding solutions, including online prescription refills, to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.


For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online-refill-button What is Ketamine Nasal Spray prescriptions used for? Los Angeles California Online Pharmacy

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.