Neuroinflammation Treatment with LDN
Neuroinflammation refers to triggering of the brain’s immune system because of an inflammatory challenge. The process can be kickstarted because of an infection, injury, neurogenerative disease, aging, or exposure to some toxin.
American Integrative Pharmacy (AIP), led by Dr. Neema Yazdanpanah, provides reliable and judicious compounding medications to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and online nationwide.
LDN and Neuroinflammation
Low dose naltrexone or LDN reduces inflammation in the brain which is the result of over-active microglia. Microglia is an important line of defense. It is a kind of glial cell present in the brain and spinal cord or the Central Nervous System (CNS). These cells are activated because of an assault on the CNS. They release cytokines or a type of inflammatory substance that works towards destroying foreign invaders.
Microglia return back to their normal resting state when the assault is over. However, repeated toxins, infection, emotional blows, injury, and traumas can cause the microglia to become hyperactive. This makes the brain stay in a constant state of inflammation.
Boost Pain Managing Chemicals
LDN causes an increase in enkephalin and endorphin, that makes the body feel less pain. Enkephalin and endorphin molecules work on the brain’s opioid receptors that produce pain reliving analgesia. Your body’s immune response is also normalized by an increase in endorphins. Additionally, LDN increases Met-5, a type of opioid growth factor that regulates the division of cells in both normal and abnormal cells. This is one of the reasons why LDN is helpful with cancer.
Pain sensitivity and fatigue can be increased because of inflammatory cytokines that are triggered because of an assault on the CNS. This can cause other inflammation to occur throughout the body as well. Scientists and doctors are still not sure what causes neuroinflammation, but they suspect that activation of glial cells may be involved.
This explains a 2010 study of the effects of LDN treatment in women that resulted in a 30% reduction in the severity of symptoms. Patients with Crohn’s Disease saw an even stronger response to LDN. More than 80% patients witnessed significant improvements.
The effect of LDN on chronic pain due to autoimmune conditions because of psoriatic arthritis works in a similar fashion. It suppresses glial cells and reduces inflammation. Correlating with this, there is a lot of evidence that suggests LDN to retain regular dosing activity and blocking opioid receptors. This causes the body to release increased endorphins and reduce pain.
Suppressing Inflammatory Response
LDN research suggests that the drug has the capacity to suppress inflammatory microglia response. Multiple sclerosis, fibromyalgia, complex regional pain syndrome, cancer, and Crohn’s disease are a few inflammatory conditions that have been shown to benefit from LDN.
Low dose naltrexone is useful in blocking opioid receptors, which means you cannot take narcotic pain medication with it. There are no side effects to LDN and is well-tolerated by most people. You may experience mild sleep disruption or excessive dreaming in the initial days.
AIP provides advanced compounding pharmacy solutions, including online prescription refills to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and online nationwide.
Pharmacy’s Online Compound Prescriptions
American Integrative Pharmacy is located in Torrance, CA serving residents in and around Orange County, Los Angeles, Long Beach, Lomita and surrounding areas. Online prescription sales are available across the US.