Knowing All About AntipyrineAntipyrine is a pharmacy medication that helps reduce or alleviate pain, swelling, and inflammation in the ear. Doctors may also prescribe it as an agent to soften wax build-up in the ear making it easier to remove. Antipyrine is not an antibiotic drug.

It assists only in relieving conditions of the ear but will not be effective against an infection. If the physician suspects an infection, they will prescribe a suitable antibiotic to address the infection.

In combination, antipyrine and benzocaine otic can help decrease pain and uneasiness in the ear. American Integrative Pharmacy (AIP), led by the committed Dr. Neema Yazdanpanah, provides compounding medications to patients in Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide.

Medication Use

Antipyrine and benzocaine otic are available in the form of a solution (liquid) for application in the ear. If antipyrine and benzocaine otic are used for pain relief, it is typically placed every one to two hours in the ear as required. When this combination is used for ear wax removal, it is usually applied three times every day for around two to three days.

Patients must follow the instructions on the prescription label carefully, and ask the physician or pharmacists for clarifications for any part that they do not comprehend. Patients should use antipyrine and benzocaine otic only as directed.

Antipyrine and benzocaine otic is intended only for use in the ears.

Patients should use the eardrops as follows:

  • Hold the bottle in their hands for a minute or two to warm the liquid
  • Apply the directed number of drops in the ear
  • Not touch the tip with their ear, fingers, or any other surface
  • Use the drops to moisten a small cotton piece and place into the outer part of the ear
  • Repeat the steps 2 to 4 for the other ear, if needed

Antipyrine may also be prescribed for alternate uses. Patients should talk to their physician or pharmacist for more information.

Special Precautions

Prior to taking antipyrine and benzocaine otic, patients should:

  • Inform the physician if they are allergic to antipyrine, benzocaine or any other drugs.
  • Inform the physician and pharmacist about the other prescription and non-prescription medicines, supplements, vitamins, or herbal products that they are taking or intend to take.
  • Inform the physician if they have a hole in the ear tube(s) or ear drum(s). In this case, the physician may not prescribe antipyrine.
  • Inform the physician if she is pregnant, intends to become pregnant or is breastfeeding. Patients who become pregnant while using antipyrine should consult their doctor.

Missed Dose

Antipyrine is typically applied as necessary. If the physician prescribes regular use of antipyrine and benzocaine otic, the patients should use the missed dose as soon as they remember. But if it is almost time for the next dose, they can skip the missed dose and administer the routine dose as per schedule. Patients should not use extra medicine to compensate for the missed dose.


Patients should call the doctor immediately if any of the below rare but severe side-effects occur in or around the ears:

  • Burning
  • Stinging
  • Redness
  • New pain

The honorable AIP receives patients from Long Beach, Torrance, Los Angeles, South Bay Orange County, Southern California areas, and nationwide for compounded medications.

For more information on compound pharmacy medications available or to make an online prescription purchase, please click here or call Toll Free 1-855-247-7948.

Online refill button

American Integrative Pharmacy is located in Lomita, CA serving residents in and around Orange County, Los Angeles, Long Beach, Torrance and surrounding areas. Online prescription sales are available across the US.

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